Test out what you know about the urinary system by taking this quiz. But reabsorption is limited in this segment. Vasa recta is highly reduced in the cortical nephrons. The descending limb of the Loop of Henle is permeable to water so water diffuses out of the descending limb into the interstitial fl uid. Filtrate next passes through the ascending limb of the loop of Henle as it exits the medulla. This leads to the descending limb, then to the ascending limb, of the loop of Henle. The loop of Henle concentrates the salts which are added to the urine for excretion, creating a high solute concentration found in the medulla. The ascending limb of loop of Henle is divided into 2 segments: Lower end of ascending limb is very thin and is lined by simple squamous epithelium. A: The ascending limb of the loop of Henle functions to dilute the filtrate by removing solutes. Some authors consider the nephron loop to be synonymous with the loop of Henle, while other authors include the proximal straight tubule, nephron loop and distal straight tubule in this term. In this context, the thin ascending limb of loop of Henle would be included. The loop of Henle has two distinct sections: a descending and ascending limb. The Loop of Henle contributes to the absorption of approximately 25% of filtered sodium and can be targeted by diuretic therapy. more permeable to water, water reabsorption increases. The loop of Henle has two distinct sections: a descending and ascending limb. Henles Loop: Reabsorption is minimum in its ascending limb. secretion reabsorption henle loop nephron along different parts figure physiology medical Histologically, cells of the DCT can be differentiated from cells of the proximal convoluted tubule: The loop of Henle has a thin descending limb, a thick ascending limb and a thin ascending limb. Have you studied the chapter urinary system? Distal tubule Na + /K + /2Cl co-transport is inhibited by loop diuretics. Additionally, the loop of Henle invades the renal medulla, which is naturally high in salt concentration and tends to absorb water from the renal tubule and concentrate the filtrate. In this context, the thin ascending limb of loop of Henle would be included. Overall, it is a Enter the email address you signed up with and we'll email you a reset link. The descending limb is permeable to water, not solutes; the opposite is true for the ascending limb. In fact, water absorption increases as the loop descends deeper into the kidney and the tissue becomes hypertonic. To check your knowledge about the topic, take this urinary system quiz. Also in animals, kidneys use ATP for the active transport of sodium chloride out of the ascending limb of the loop of Henle in order to lower water potential in the surrounding tissues. 12. Fill in the gaps: (a) Ascending limb of Henles loop is _____ to water whereas the descending limb is _____ to it. More specifically, the descending limb is highly permeable to water, less permeable to solutes, while the ascending limb is the opposite. The descending limb of the loop of Henle is relatively impermeable to solutes and freely permeable to water. As filtrate passes down Henles loop, osmolality increases, due to osmosis of water into the hypertonic interstitium. The descending limb of the loop of Henle is permeable to water but impermeable to solutes, due to the presence of aquaporin 1 in its tubular wall. 2. This region regulates ion and pH balance. The DCT is the site for the activity of most hormones that regulate kidney function.

Before moving into the loop of henle the filtrate in the nephron is isosmotic with the blood. Countercurrent Multiplication in the Loop of Henle. The functioning of the urinary system involves selected organs, but the main one is the kidney.

This concentrates the filtrate as it moves down. A. thick segment is permeable to water A minute vessel of the network that runs parallel to the Henles loop forming a U shaped vasa recta.

However, this region plays a significant role in the maintenance of high osmolarity of medullary interstitial fluid. The DCT is the site for the activity of most hormones that regulate kidney function. But reabsorption is limited in this segment. more permeable to water, water reabsorption increases. Loop of Henle to the DCT. As the tubule grows, more of the glomerular filtrate is reabsorbed and less reaches the macula densa (MD) at the end of Henles loop. The filtrate moves down the falling limb, and water osmoses out due to the water potential gradient. (a) True (b) False. The DCT is the site for the activity of most hormones that regulate kidney function. Some sources simply refer to a "thin limb". The loop of Henle has a thin descending limb, a thick ascending limb and a thin ascending limb. Sodium and chloride ions are pumped out of the ascending limb to create a water potential gradient.

Sodium and chloride ions are pumped out of the ascending limb to create a water potential gradient. Enter the email address you signed up with and we'll email you a reset link.

The ascending limb of the loop of Henle is permeable to water. It has tightly packed columnar cells which display reversed polarity and may monitor the osmolarity of blood. Also called the loop of Henle, the Henles loop carries both descending limb of loop of henle and ascending limb of loop of Henle. Sodium chloride is actively transported from the thick portion of the ascending limb without accompanying water so that an osmotic gradient of approximately 200 mOsm/kg is generated. Sodium and chloride ions are pumped out of the ascending limb to create a water potential gradient. Since the electrolytes get reabsorbed at the ascending loop of Henle, the filtrate gets diluted as it moves towards the ascending limb. The ascending limb feeds into the distal convoluted tubule which leads into the collecting duct system, the first portion of which is the collecting tubule, followed by the cortical collecting duct and then the medullary collecting duct. The ascending limb is highly permeable to salts than water so during the absorption of these salts, more water exits the descending limb which in turn creates concentrated urine. The Loop of Henle contributes to the absorption of approximately 25% of filtered sodium and can be targeted by diuretic therapy. (a) True (b) False. Additionally, the loop of Henle invades the renal medulla, which is naturally high in salt concentration and tends to absorb water from the renal tubule and concentrate the filtrate. The point where DCT contacts the cortical thick ascending limb of the loop of Henle is called macula densa. The descending limb of the loop of Henle is relatively impermeable to solutes and freely permeable to water. The descending limb of the loop of Henle is relatively impermeable to solutes and freely permeable to water. As the liquid returns through the thin ascending limb, sodium chloride diffuses out of the tubule into the surrounding tissue, where its concentration is lower. The first segment of the loop, the thin descending limb, is permeable to water, and the liquid reaching the bend of the loop is much richer in salt and urea than the blood plasma is. ' '' ''' - -- --- ---- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- ----- Distal tubule If you can't answer any of the questions, you can learn something new. B: The cuboidal cells of the distal tubule and collecting duct function to remove water and additional solutes. It has tightly packed columnar cells which display reversed polarity and may monitor the osmolarity of blood. This causes the glomerular filtration rate (GFR) to increase through the normal physiologic action of the tubuloglomerular feedback (TGF) system . This leads to the descending limb, then to the ascending limb, of the loop of Henle. Ions are reabsorbed from tubular fluid by a Na + /K + /2Cl co-transporter in the apical membranes of the thick ascending limb. Thus, water moves across the tubular wall into the medullary space, making the filtrate hypertonic (with a lower water potential). As filtrate passes down Henles loop, osmolality increases, due to osmosis of water into the hypertonic interstitium. Countercurrent Multiplication in the Loop of Henle. This causes the glomerular filtration rate (GFR) to increase through the normal physiologic action of the tubuloglomerular feedback (TGF) system . The descending limb is permeable to water but impermeable to an electrolyte, while the ascending limb is permeable to electrolytes but impermeable to water. Activation of the V2 receptor results in insertion of the water channel aquaporin-2 in the luminal membrane of the collecting duct, thus making it more permeable to water. Henle's Loop. The descending limb is permeable to water but impermeable to an electrolyte, while the ascending limb is permeable to electrolytes but impermeable to water. The loop has a sharp bend in the renal medulla going from descending to ascending thin limb.

The point where DCT contacts the cortical thick ascending limb of the loop of Henle is called macula densa. Since the electrolytes get reabsorbed at the ascending loop of Henle, the filtrate gets diluted as it moves towards the ascending limb. Henles Loop: Reabsorption is minimum in its ascending limb. The countercurrent multiplier functions because of two factors: (1) the descending limb of the loop of Henle is relatively impermeable to solutes and freely permeable to water, and (2) the ascending limb is permeable to solutes but not to water. Additionally, the loop of Henle invades the renal medulla, which is naturally high in salt concentration and tends to absorb water from the renal tubule and concentrate the filtrate. In the loop of Henle, the permeability of the membrane changes. The filtrate moves down the falling limb, and water osmoses out due to the water potential gradient. In contrast, in the ascending limb, sodium permeability is high, but water permeability is low. A. thick segment is permeable to water Also called the loop of Henle, the Henles loop carries both descending limb of loop of henle and ascending limb of loop of Henle. This is the filtrate that continues to the ascending limb. In contrast, in the ascending limb, sodium permeability is high, but water permeability is low. The ascending limb then leads into the distal convoluted tubule or DCT, also known as the second convoluted tubule. Imagine a situation in which the number of urea leak channels increased dramatically in the ascending limb of the loop of Henle.